Polyphenol gentiopicroside is extraction of component a regeneration effect on human skin active components from various plant gentiopicroside in. It is an activation of the proteasome system effectively, can be re activated cell regeneration plant. If the skin with polyphenol gentiopicroside processing, when the younger then, initial symptoms reached by the activation of proteasome function can delay aging. Through this effective degradation of damaged proteins (detoxification), cell division ability to rebuild, and to keep the dynamic balance of long; its resistance to ultraviolet light caused by aging or oxidative stress was improved.

Plant bitter glycoside extract treated keratinocytes to proteasome proteolytic activity doubled. Alone with corresponding keratinocyte polyphenol bitter glycosides treatment even more activation of proteasome strong. The active ingredient in an impressive way of promoting the proteasome activity; make better degradation of damaged proteins.